What Is Doxolin 400 Mg?
Doxolin 400 mg is a common brand name for a medication whose active ingredient is Doxofylline. It belongs to a class of drugs called bronchodilators and is primarily used for the long-term management of Asthma and chronic respiratory diseases.
Here is a breakdown of the key information about Doxolin 400 mg:
Active Ingredient: Doxofylline (400 Mg strength)
Manufacturer: Zydus Cadila Ltd.
Drug Class: Bronchodilator (specifically, a methylxanthine derivative)
Dosage: The typical adult dose is 400 Mg once or twice daily, as prescribed. Dosing must be tailored by a doctor.
Uses
Doxolin is a maintenance therapy drug, meaning it is taken regularly to control symptoms and prevent flare-ups, not for immediate relief of a sudden breathing attack.
- For Curing Asthma
The use of Doxolin 400 mg works to relax the muscles of the airways and does not cause choking. This means that the patient does not have any difficulty breathing or suddenly suffers from other issues of asthma, like wheezing or coughing.
- For COPD
Used to improve airflow and lung function in patients with chronic bronchitis and emphysema (which are components of COPD).
How It Works
It works by relaxing the smooth muscles of the airways in the lungs, which causes the airways to widen. This makes breathing easier and helps relieve symptoms like wheezing, shortness of breath, and coughing.
The main way Doxofylline achieves its effect is by working on an enzyme inside the cells of your lungs:
Smooth Muscle Relaxation: Increased cAMP levels trigger asthma a cascade of events that cause the relaxation of the smooth muscles surrounding the airways.
Anti-Inflammatory Properties: By modulating the activity of immune cells (like mast cells, eosinophils, and neutrophils), Doxofylline helps to dampen the overall inflammatory response in the airways.
How To Take
Here are the key instructions for how to take Doxolin 400 mg:
- To use Doxolin 400 mg, you will only need to swallow the pill with water.
- Use the pill same time daily as it gives the most effects.
- For each time, follow the dose given by the doctors and keep using the medicine until the end of the tenure.
Dosage
The typical adult dose is 400 Mg once or twice daily, as prescribed. Dosing must be tailored by a doctor.
Dose for children
Use of this pill is not safe till your child has completed 18 years, as it is not safe for children or teenagers.
Missed Dose
It takes time for the effects of the medicine to get active and start showing ample changes. Most of the time, the effects of the medicine peak only when you take it daily after a week or so.
However, in the meantime, if you miss taking too many doses, you may not feel any changes at all.
Overdose
There is a certain dose of Doxolin 400 Mg Australia, which is safe for the patient to use, beyond which the excess of the medication results in side effects.
Precautions & Warnings
Inform your doctor immediately if you have a history of any of these conditions, as the drug may need to be avoided or the dosage adjusted:
Pregnancy
There is limited data on its safety during pregnancy. It should only be used if the potential benefits clearly outweigh the risks, and only under a doctor’s guidance.
Breastfeeding
Using the Doxolin 400 mg pills can affect the health of the other person, or you are an infant too. Some studies show that the effects of the medicine can pass down your breast milk.
Congestive Heart Failure (CHF)
Patients with CHF have reduced drug clearance, meaning the medication can stay in the system longer, potentially leading to toxic levels.
Liver Disease or Kidney Problems
Since the drug is metabolised by the liver and excreted by the kidneys, impairment in these organs can lead to the drug accumulating in the body and potentially causing toxicity.
Addictions
Whether it is asthma or COPD, using alcohol or any other addictive item can only make its effects more intense. This means that the medicine may not work fully or help cure the issue completely. To have the most effect, you need to get rid of such habits completely.
Avoid Taking Doxolin 400 Mg
With other health issues
- Bronchi or lung infections
- Nasal or throat infections
- Low immunity
- Autoimmune conditions
- Arthritis
- AIDS
- UTIs
You must tell the doctors if you have taken such medicine with the same composition before and have ever had any allergic reactions in your body. In this case, avoid taking the Doxolin 400 mg too.
Side Effects
These side effects are most frequently reported and often subside as your body adjusts to the medication:
- Headache
- Nausea
- Vomiting
- Stomach issues like indigestion and bloating.
While less frequent, these side effects can be more serious and require medical attention. Contact your doctor immediately if you experience any of the following:
- Palpitations
- Tachycardia
- Hypotension
The side effects are often related to the stimulating effects of the xanthine compound on the nervous system and the gastrointestinal tract.
Storage
Store the tablets in a cool, dry place. Avoid extreme heat or cold. Always keep Doxolin 400 mg and all medications out of the sight and reach of children and pets.
Conclusion
A medicine called Doxolin 400 mg is a preventive medicine given to patients with COPD in order to control sudden or severe symptoms of the disease, so they can slowly return to a normal life.
FAQs
Q. Is Doxolin 400 mg a rescue inhaler?
No, absolutely not. Doxolin is a preventative, long-term medication that does not work fast enough to relieve a sudden, acute breathing attack. You must always keep a prescribed inhaler on hand for emergencies.
Q. What is the most important warning about Doxolin?
The most important warning is that it is not a rescue drug for acute shortness of breath. You must have a rescue inhaler available.
Q. Does Doxolin 400 mg interact with smoking?
Yes. Because smoking increases the liver’s metabolism of Doxofylline, it can significantly reduce its effectiveness. The dose of your medication may need to be adjusted if you smoke.
Q. What is the best time of day to take Doxolin 400 Mg?
The medication is often taken in the evening or after dinner to manage symptoms (like coughing and wheezing) that can worsen at night.





