What Is Mesacol 500 Mg?
Mesacol 500 mg contains Mesalamine (also known as Mesalazine), which belongs to a class of drugs called aminosalicylates. It is primarily used to treat inflammatory bowel diseases (IBD) like ulcerative colitis and sometimes Crohn’s disease.
However, with the use of Mesacol 500 mg, the patient can finally get some relief from some of the usual signs of both these disorders, like-
- Pain around the lower belly area
- Swelling
- Bleeding
- Diarrhea
The action of the medicine is to reduce the inflammation in the bowel, which also addresses the problems. To be able to begin using this pill, you need to go to a doctor.
Manufacturer
Sun Pharma Ltd is the company that holds the license and manufacturing rights to the brand of Mesacol.
Composition
Mesalazine is the only chief component that is present in the Mesacol 500 mg pills.
How It Works
The exact way mesalamine works is still being studied, but it is believed to reduce inflammation through several pathways:
Blocking Prostaglandins: It stops the production of certain natural substances (prostaglandins and leukotrienes) that cause swelling and pain in the intestinal lining.
Antioxidant Properties: It acts as a “scavenger,” neutralizing harmful free radicals that damage the tissue in your colon.
Immune Modulation: It helps dampen the overactive immune response in the gut that leads to the sores and ulcers seen in colitis.
How To Use
- To use the medicine, you just need to orally swallow the whole pill.
- The right time would be before taking any medicine, right in the early morning hours.
- When taking it, you do not need to break, crush, or chew the medicine.
- Simply swallow the tablet with water.
Dosage
For Ulcerative Colitis
- For curing ulcerative colitis, the doctors use of 500 mg medicine once per day.
- Usually, your prescription may run for a few weeks to a couple of months based on how severe the issue is.
For Crohn’s Disease
- The Mesacol 800 mg dose is again used only once each day.
- The course can run up to three to 4 weeks, depending on the health condition.
Further Dosage Instructions-
- Do not miss taking your dose each day.
- In addition, the doctors prefer that you take your daily pill at the same time each day.
- Avoid increasing the dose or frequency of use unless the doctors approve it.
- Remember that this can cause side effects in the patient.
Warnings And Precautions Before It
Use Of Other Medicines
Mesalazine is an FDA-approved dose, but despite this, the drug tends to interact with other classes of medicines. These pills are-
- Medicines to cure liver or kidney disorders.
- Pills taken during pregnancy or after childbirth.
- Pills to cure other stomach and intestinal infections.
With Other Health Issues
Tell the doctors if you have other health issues like-
- Stomach disorders
- Peptic ulcers
- GERD
- Colon infections
Allergic Tendency
It is rare, but patients may have a natural allergic tendency with the use of Lesalazine.
In this case, you can show signs of-
- Inflammation
- Swelling
- Bruising
- Rashes
- Fever
- Sore throat
- Severe tiredness
Tell the doctors urgently in case such side effects occur anyhow.
Caution Tips
Driving
Avoid driving a car after using the pill, especially if you get lightheadedness or a headache, and nausea.
Alcohol
As per studies, the effects of long-term use of alcohol can cause inflammation in the stomach, intestine, or colon to increase.
We highly recommend that you give up such habits before taking the Mesacol 500 mg pill as a regular dose. We also advise patients to avoid any form of narcotic drugs like cocaine.
Breastfeeding
Even though there are limited studies done in this field, results show that it is generally harmful for the baby when the mother is taking drugs like Mesacol 500 mg. The effects of Mesazoline may pass through your breast milk to the child.
Pregnancy
Some findings show harmful effects to both the health of the mother and the developing fetus with the use of Mesacol 500 mg during pregnancy.
Avoid Taking The Mesacol 500 Mg
Here are a few cases when you need to avoid using Mesacol 500 mg –
- A critical liver disorder, like liver cancer, fatty liver, or hepatitis
- A major kidney condition, such as nephritis or a kidney failure disorder
- If you had an allergic tendency when using the medicine before.
Side Effects
Most of the time, using Mesacol 500 mg is safe when the doctors have told you to use the dose. However, side effects may occur during an overdose or an interaction and cause issues.
Mild Side Effects
- Headache
- Palpitations
- Flatulence
- Vomiting
With these side effects, the issues should go away within a couple of days. Such issues can rarely get very severe over time, so you have to stop taking your daily dose.
Severe Side Effects
- Rashes
- Diarrhea
- Stomach pain
With severe side effects, the doctors will give you the option to stop using the medicine any further.
Where To Store
Store between 15°C to 25°C (59°F to 77°F). Keep the medication away from “hot spots” like the top of a refrigerator, near a stove, or in a car, as high heat can degrade the active ingredients or cause the suppository to melt.
Conclusion
The Mesacol 500 mg might just be the solution to severe internal bowel disorders like colitis and Crohn’s disease. Using the medicine can help you get rid of the signs and avoid severe complications of the disorder.
However, you have to use the medicine following certain caution steps, as there could be chances of interaction and side effects.
FAQs
Q. When To Use Mesacol 500 Mg?
The best time for using the Mesacol 500 mg is before taking any meal of the day, in the morning.
Q. Are There Any Changes To Be Made In My Diet?
Yes, mostly to cure the issues faster, the doctors will tell you to have a simple and bland diet with less fats, cholesterol, carbs, and complex proteins.
Q. Does This Medicine Cause Drug Abuse?
No, the Mesacol 500 mg is good in the sense that patients using it even for months have not had any habit-forming issues with the pill.





